ANSWER
Depending on the subject under study, various clinical research methods are employed. Here are some descriptions of many categories of clinical research.
Treatment research typically involves an intervention, such as a drug, psychotherapy, new technology, or innovative methods of radiation or surgery.

Prevention research aims to find more effective techniques to stop the onset or recurrence of illnesses. Numerous types of preventative research may examine drugs, supplements, vaccinations, minerals, or way of life modifications.
Diagnostic research is trying to find more accurate ways to diagnose a specific ailment or condition.
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Screening research aims to find the most effective methods to identify particular illnesses or disorders. Research on quality of life examines how to increase comfort and living standards for people with a chronic illnesses.
By detecting and comprehending potential connections between genes and diseases, genetic research strives to enhance disorder prediction. This study area may examine how a person’s genes influence whether they are more or less prone to acquiring a disorder. This could result in creation of therapies that are genetically tailored to each patient. Epidemiological studies look for specific populations’ trends, causes, and treatments of illnesses.

The volunteers in the specific clinical study do not spend the night at the hospital, which is a crucial point to remember. Some analysis is “inpatient,” requiring participants to spend at least one night at the hospital or research facility. Make careful to find out what is necessary for the researchers’ investigation.

QUESTION
B. Discuss the impact of a clinical practice problem on the patient or patients and the organization it affects.

1. Identify each of the following PICO components of the clinical practice problem:

• P: patient, population, or problem

• I: intervention

• C: comparison

• O: outcome

2. Develop an evidence-based practice (EBP) question based on the clinical practice problem discussed in part B and the PICO components identified in part B1.

Note: Refer to the “Appendix B: Question Development Tool” web link for information on the creation of an EBP question.

C. Select a research-based article that answers your EBP question from part B2 to conduct an evidence appraisal.

Note: The article you select should not be more than five years old.

1. Discuss the background or introduction (i.e., the purpose) of the research-based article.

2. Describe the research methodology used in the research-based article.

3. Identify the level of evidence for the research-based article using the Johns Hopkins Nursing Evidence-Based Practice (JHNEBP) model.

Note: Refer to the “Appendix E: Research Evidence Appraisal Tool” web link for information on how to level a research-based article.

4. Summarize how the researcher analyzed the data in the research-based article.

5. Summarize the ethical considerations of the research-based article. If none are present, explain why.

6. Identify the quality rating of the research-based article according to the JHNEBP model.

Note: Refer to the “Appendix E: Research Evidence Appraisal Tool” web link for information on how to establish the quality rating.

7. Analyze the results or conclusions of the research-based article.

a. Explain how the article helps answer your EBP question.

D. Select a non-research-based article from a peer-reviewed journal that helps to answer your EBP question from part B2 to conduct an evidence appraisal.

Note: The article you select should not be more than five years old.

1. Discuss the background or introduction (i.e., the purpose) of the non-research-based article.

2. Describe the type of evidence (e.g., case study, quality improvement project, clinical practice guideline) used in the non-research-based article.

3. Identify the level of evidence in the non-research-based article using the JHNEBP model.

Note: Refer to the “Appendix F: Non-Research Evidence Appraisal Tool” web link for information on how to level the non-research-based article.

4. Identify the quality rating of the non-research-based article according to the JHNEBP model.

5. Discuss how the author’s recommendations in the non-research-based article help answer your EBP question.

E. Recommend a practice change that addresses your EBP question using both the research-based and non-research-based articles you selected for part C and part D.

1. Explain how you would involve three key stakeholders in supporting the practice change recommendation.

2. Discuss one specific barrier you may encounter when implementing the practice change recommendation.

3. Identify one strategy that could be used to overcome the barrier discussed in part E2.

4. Identify one outcome (the O component in PICO) from your EBP question that can be used to measure the recommended practice change.

F. Acknowledge sources, using APA-formatted in-text citations and references, for content that is quoted, paraphrased, or summarized.

G. Demonstrate professional communication in the content and presentation of your submission.

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